Information surrounding COVID-19 has been all over the place; navigating it is reminiscent of traversing a maze in a dream. But among the virus’ well-established idiosyncrasies that have manifested repeatedly is the fact that “angiotensin-converting enzyme II (ACE2) is the cell receptor of SARS-CoV2 and the main route for receptor-mediated entry of the virus into the human host,” as a team of Canadian researchers recently pointed out. [1] The researchers explain, “ACE2 expression in oral, lung, and intestinal epithelia may thus constitute important routes of SARS-CoV2 entry into hosts.” Such expression is associated with susceptibility and more serious disease.

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